Brand Name: Xenical®
Active Ingredient: orlistat
Strength(s): 120mg
Dosage Form(s): Capsule
Company Name: Roche
Availability: Prescription only
Date Approved by FDA: April 23, 1999

What is Xenical used for?

Xenical is used to help obese people who fit certain weight and height requirements lose weight and maintain weight loss. Xenical works in your intestines, where it blocks some of the fat you eat from being absorbed. This undigested fat is then eliminated in your bowel movements. Use Xenical together with a reduced-calorie diet. The weight management effects of Xenical continue only as long as you are taking it.

Who should not take Xenical?

You cannot take Xenical if you:

• have problems absorbing food
• have gallbladder problems
• are pregnant, or breast-feeding a child

People with certain kidney problems may not be able to take Xenical.

General Precautions with Xenical:

• Your daily intake of fat should be evenly divided over 3 main meals.
• Xenical can decrease the absorption some fat-soluble vitamins and beta-carotene. Therefore when being treated with Xenical, take a multivitamin supplement that contains vitamins D, E, K, and beta-carotene. Take your multivitamin once a day at least 2 hours before or after taking Xenical, such as bedtime.
• Review all medications that you are taking with your health care provider, including those that you take without a prescription. If you are taking cyclosporine you may have to be monitored more closely.
• If you are diabetic, Xenical may affect your blood sugar control. See your doctor regularly for monitoring and treatment adjustments.

What should I tell my doctor or health care provider?

Tell your health care provider if you are trying to become pregnant, are already pregnant, or are breast-feeding.

What are some possible side effects of Xenical? (This is NOT a complete list of side effects reported with Xenical. Your health care provider can discuss with you a more complete list of side effects.)  

• Oily spotting
• Gas with discharge
• Urgent need to have a bowel movement
• Oily or fatty stools
• Oily discharge
• Increased number of bowel movements
• Inability to control bowel movements

Posted: 9/3/99
Revised: 11/16/00