Brand Name: NeoTect Kit®
Active Ingredient: Technetium Tc 99m Depreotide Injection
Strength(s): Depreotide containing approximately 15-20 mCi of Technetium Tc 99m and 50µg of Depreotide
Dosage Form(s): Injection
Company Name: Diatide Inc..
Availability: Prescription only
Date Approved by FDA: August 3, 1999

What is NeoTect used for?

NeoTect is a radioactive imaging test used to evaluate certain lung lesions in patients who test positive for lung lesions using other imaging tests (e.g., CT or MRI) and have been diagnosed with cancer or have a strong likelihood of cancer. NeoTect identifies certain cells that may be associated with lung cancer and sometimes with other conditions. Special Warnings with NeoTect:

If there is a history of drug reactions or allergies, emergency equipment and health care professionals trained to recognize and treat severe allergic reactions should be available when NeoTect is given.

General Precautions with NeoTect:

• The contents of NeoTect Kit are mixed with a radioactive solution by a health care practitioner. NeoTect is a radioactive drug and must be handled with care. Appropriate safety measures should be taken to minimize exposure to clinical personnel and to the patient. NeoTect should be given only by doctors who are licensed to use radioactive drugs.
• If you have diabetes or have been diagnosed with tumors in the cells that secrete insulin, tell your doctor. When you are given NeoTect, tell your doctor if you experience symptoms of very low blood sugar.
• To decrease the radiation absorbed by the bladder, you should drink at least an 8 oz. glass of water before NeoTect injection to ensure frequent urination during the first few hours after the test. The radioactive drug generally is eliminated over about 24 hours, with the majority occurring during the first 4 hours.
• If you are unable to control your urination completely, your doctor may insert a bladder catheter (tube) to minimize the risk of radioactive contamination of your clothing and bed linen.
• To protect yourself and others, you need to take the following precautions for 12 hours after your dose of NeoTect:
  • Use a toilet and not a urinal
  • Flush the toilet several times after each use
  • Clean up any spilled urine immediately
  • Wash your hands thoroughly after each time you go to the toilet
  • If blood, urine, or feces gets onto clothing or linens, the clothing or linens should be washed separately

What should I tell my doctor or health care provider?

Tell your health care provider if you are trying to become pregnant, are already pregnant, or are breast-feeding. If you are breast-feeding, it is recommended that you switch to infant formula while NeoTect is given and until the radioactive drug is eliminated from your body.

What are some possible side effects of NeoTect? (This is NOT a complete list of side effects reported with NeoTect. Your health care provider can discuss with you a more complete list of side effects.)  

NeoTect is generally well tolerated. Your health care provider can discuss with you a more complete list of possible side effects

Posted 09/27/99
Updated: 3/15/01, 12/29/04