Directory of Drugs: ComtanŽ - entacapone
Brand Name: Comtan®
Active Ingredient: entacapone
Dosage Form(s): Tablets
Company Name: Orion Corporation
Availability: Prescription only
Date Approved by FDA: October 19, 1999
What is Comtan used for?
Comtan is used together with carbidopa/ levodopa to treat people with Parkinson’s disease that experience the signs and symptoms of end-of-dose "wearing-off".
Comtan’s effectiveness has not been proven in people with Parkinson’s disease that do not experience end-of-dose "wearing-off".
- Comtan should be used with caution in patients with liver problems.
- Do not stop taking Comtan without first discussing it with your doctor.
- Do not drive a car or operate heavy machinery until you know how you will react to Comtan.
- Be especially careful when taking other sleep-inducing drugs while using Comtan
What should I tell my doctor or health care provider?
- Because certain other medications can interact with Comtan, review all medications that you are taking with your health care provider, including those that you take without a prescription.
- Check with your health care provider to make sure that you are not taking certain types of monoamine oxidase (MAO) inhibitors.
- Tell your health care provider if you are trying to become pregnant, are pregnant, or are breast-feeding.
What are some possible side effects of Comtan? (This is NOT a complete list of side effects reported with Comtan. Your health care provider can discuss with you a more complete list of side effects.)
Some of the side effects listed below may not appear for up to twelve weeks.
- Abnormal jerky movements
- Discolored (brownish orange) urine
- Abdominal pain
- Dizziness or fainting especially upon quickly standing or going from a laying down to an upright position
Individuals treated with Comtan should tell their health care provider right away if they develop any of the following symptoms:
- Severe diarrhea
- Muscle pain or prolonged rigidity
- High fever
Date created: June 7, 2000; Last updated: December 29, 2004
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